Adaptation of human adipose tissue to hypocaloric diet

Brown adipose tissue activity in hypocaloric-diet fed lactating rats.

Hypocaloric diet feeding reduced the mitochondrial protein content and whole tissue GDP-binding in interscapular brown adipose tissue from both virgin and lactating rats. A reduction in brown fat lipoprotein lipase activity was also detected in underfed virgin and lactating animals. These results indicate that lactation in the rat, even though it produces a reduction in brown fat activity, does...

Adaptation of Horsesickness Virus to Tissue Culture

Effect of diet on human adipose tissue metabolism.

Adipose tissue is, in one sense, the tissue most affected by diet. As the ultimate reservoir for energy storage, its mass reflects an integration of energy imbalance during the bearer’s life. Diet also has qualitative effects on adipose tissue: for instance, the pattern of adipose tissue triacylglycerol (TAG)-fatty acids reflects the dietary fatty acid pattern (Hirsch, 1965; Jacobsen et af. 198...

Sympathetic Neural Adaptation to Hypocaloric Diet With or Without Exercise Training in Obese Metabolic Syndrome Subjects

OBJECTIVE Sympathetic nervous system (SNS) overactivity contributes to the pathogenesis and target organ complications of obesity. This study was conducted to examine the effects of lifestyle interventions (weight loss alone or together with exercise) on SNS function. RESEARCH DESIGN AND METHODS Untreated men and women (mean age 55 +/- 1 year; BMI 32.3 +/- 0.5 kg/m(2)) who fulfilled Adult Tre...

Capacity for moderate exercise in obese subjects after adaptation to a hypocaloric, ketogenic diet.

To study the capacity for moderate endurance exercise and change in metabolic fuel utilization during adaptation to a ketogenic diet, six moderately obese, untrained subjects were fed a eucaloric, balanced diet (base line) for 2 wk, followed by 6 wk of a protein-supplemented fast (PSF), which provided 1.2 g of protein/kg ideal body wt, supplemented with minerals and vitamins. The mean weight lo...